Yang Shangda

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个人简介
个人信息 姓 名:杨尚达 出生年月:1990.03
联系电话:15822740445 邮 箱:yangshangda@tmu.edu.cn
教育背景 博/硕士研究生:2013-2018 天津医科大学(五年硕博连读)
医学生物化学与分子生物学专业
表观遗传学方向
导师—石磊教授
本 科:2009-2013 临沂大学 生物技术专业
发表论文
1. USP52 Acts as a Deubiquitinase and Promotes Histone Chaperone ASF1A Stabilization. NATURE COMMUNICATIONS. (2018) 9:1285 | DOI: 10.1038/s41467-018-03588-z (IF= 12.124, 第一作者).
2. SIRT7 is a histone desuccinylase that functionally links to chromatin compaction and genome stability. NATURE COMMUNICATIONS. 20 Jul 2016. 7:12235 | DOI: 10.1038/ncomms12235. (IF= 12.124, 第二作者).
3. Histone demethylase KDM5B is a key regulator of genome stability. PNAS. May 13, 2014. 111:7096-7101. (IF= 9.661, 第二作者).
个人技能
计算机: 熟练使用Office, Photoshop, SPSS, Graphpad Prism5, FlowJo, Adobe Illustrator, Image J, Image pro plus, Primer Premier5, DNAstar, Clustal X等图像处理和专业分析应用软件,能够熟练制作SCI要求的图表和专业课件;
实验技能:熟练掌握亲和层析,免疫共沉淀(Co-IP),免疫荧光(IF),免疫组织化学(IHC),蛋白质纯化,高效液相色谱(FPLC),染色质免疫共沉淀(ChIP),细胞培养等相关实验。
获奖情况
1 天津医科大学第一届“基础医学卓越人才计划研究生学术论坛”壁报二等奖。
2 天津医科大学“基础医学院2017年度学术年会”优秀论文奖。
3 天津医科大学2018届优秀毕业博士研究生。

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About Us

Our team member is young and energetic.Our laboratory primarily focuses on both genetic and epigenetic mechanisms in hematopoietic stem and progenitor cells, with each project guided by methods intended to elucidate basic principles as well as practical solutions. Through broadly collaborative approaches, We also committed to training hematologists and stem cell biologists and to building strong and competitive hematology and stem cell research programs that will ultimately benefit the patients.