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  1. Zhang JP, Li XL, Neises A, Chen W, Hu LP, Ji GZ, Yu JY, Xu J, Yuan WP, Cheng T*, Zhang XB*(co-corresponding authors). Different Effects of sgRNA Length on CRISPR-mediated Gene Knockout Efficiency. Sci Rep. 2016 Jun 24;6:28566. doi: 10.1038/srep28566.
  2. Wen W, Zhang JP, Xu J, Su RJ, Neises A, Ji GZ, Yuan W, Cheng T*, Zhang XB* (co-corresponding authors). Enhanced Generation of Integration-free iPSCs from Human Adult Peripheral Blood Mononuclear Cells with an Optimal Combination of Episomal Vectors. Stem Cell Reports. 2016 May 3. pii: S2213-6711(16)30030-3. doi: 10.1016/j.stemcr.2016.04.005.
  3. Cheng H, Liu Y, Jia Q, Ma S, Yuan W, Jia H, Cheng T. Novel regulators in hematopoietic stem cells can be revealed by a functional approach under leukemic condition. Leukemia. 2016 May 2. doi: 10.1038/leu.2016.118.
  4. Zheng Y, Zhang H, Wang Y, Li X, Lu P, Dong F, Pang Y, Ma S, Cheng H, Hao S, Tang F, Yuan W, Zhang X, Cheng T. Loss of Dnmt3b accelerates MLL-AF9 leukemia progression. Leukemia. 2016 May 2. doi: 10.1038/leu.2016.112.
  5. Wang Y, Gao A, Zhao H, Lu P, Cheng H, Dong F, Gong Y, Ma S, Zheng Y, Zhang H, Zhang Y, Xu J, Zhu X, Yuan W, Zhang X, Hao S, Cheng T. Leukemia cell infiltration causes defective erythropoiesis partially through MIP-1α/CCL3. Leukemia. 2016 Apr 25. doi: 10.1038/leu.2016.81.
  6. Zhao Y, Zhou J, Liu D, Dong F, Cheng H, Wang W, Pang Y, Wang Y, Mu X, Ni Y, Li Z, Xu H, Hao S, Wang X, Ma S, Wang QF, Xiao G, Yuan W, Liu B*, Cheng T* (*co-corresponding authors). ATF4 plays a pivotal role in the development of functional hematopoietic stem cells in mouse fetal liver. Blood. 2015 Sep 17. pii: blood-2015-03-633354.
  7. Lim M, Pang Y, Ma S, Hao S, Shi H, Zheng Y, Hua C, Gu X, Yang F, Yuan W, Cheng T. Altered mesenchymal niche cells impede generation of normal hematopoietic progenitor cells in leukemic bone marrow. Leukemia. 2015 Aug 4. doi: 10.1038/leu.2015.210.
  8. Cheng H, Hao S, Liu Y, Pang Y, Ma S, Dong F, Xu J, Zheng G, Li S, Yuan W, Cheng T. Leukemic marrow infiltration reveals a novel role for Egr3 as a potent inhibitor of normal hematopoietic stem cell proliferation. Blood. 2015 Jul 17. pii: blood-2015-01-623645.
  9. Gao Y, Yang P, Shen H, Yu H, Song X, Zhang L, Zhang P, Cheng H, Xie Z, Hao S, Dong F, Ma S, Ji Q, Bartlow P, Ding Y, Wang L, Liu H, Li Y, Cheng H, Miao W, Yuan W, Yuan Y, Cheng T*, Xie XQ*. (*co-corresponding authors) Small-molecule inhibitors targeting INK4 protein p18(INK4C) enhance ex vivo expansion of haematopoietic stem cells. Nat Commun. 2015 Feb 18;6:6328. doi: 10.1038/ncomms7328.
  10. Hu L, Cheng H, Gao Y, Shi M, Liu Y, Hu Z, Xu J, Qiu L, Yuan W, Leung AY, Yang YG, Cheng T. The antioxidant N-acetyl-L-cysteine increases engraftment of human hematopoietic stem cells in immune-deficient mice. Blood. 2014 Oct 6. pii: blood-2014-03-559369.
  11. Zhu X, He F, Zeng H, Ling S, Chen A, Wang Y, Yan X, Wei W, Pang Y, Cheng H, Hua C, Zhang Y, Yang X, Lu X, Cao L, Hao L, Dong L, Zou W, Wu J, Li X, Zheng S, Yan J, Zhou J, Zhang L, Mi S, Wang X, Zhang L, Zou Y, Chen Y, Geng Z, Wang J, Zhou J, Liu X, Wang J, Yuan W, Huang G*, Cheng T*, Wang QF*. (*co-corresponding authors)  Identification of functional cooperative mutations of SETD2 in human acute leukemia. Nature Genetics. 2014 Feb 9. doi: 10.1038/ng.2894.
  12. Liu Y, Cheng H, Gao S, Zou Z, He F, Hu L, Hou D, Lu X, Li Y, Zhang H, Xu J, Kang L, Wang Q, Yuan W, Gao S*,Cheng T*. (*co-corresponding authors) Reprogramming of MLL-AF9 leukemia cells into pluripotent stem cells. Leukemia. 2014 May;28(5):1071-80.
  13. Li Y, Feng H, Gu H, Lewis D, Yuan Y, Zhang L, Yu H, Zhang P, Cheng H, Miao W, Yuan W, Cheng S, Gollin S,Cheng T. The p53-PUMA axis suppresses iPSC generation. Nature Communications 2013 Jul 19;4:2174.
  14. Shen H, Yu H, Liang PH, Cheng H, Xufeng R, Yuan Y, Zhang P, Smith CA, Cheng T. An acute negative bystander effect of γ-irradiated recipients on transplanted hematopoietic stem cells. Blood. 2012 Apr 12;119(15):3629-37.
  15. Yuan W, Sipp D, Wang ZZ, Deng H, Pei D, Zhou Q, Cheng T. Stem Cell Science on the Rise in China. Cell Stem Cell. 2012. Jan;10(1):12-15.
  16. Yu H, Shen H, Xiaochun Ping, Feng Xu, Xiaoxia Hu, Yanxin Li, Yun Ling, Jian Yu, Lin Zhang, Sean P. Garrison, Gerard P Zambetti and Cheng T. Inactivation of PUMA protects stem cells and confers long term survival in response to high dose r-irradiation. Blood 2010 Apr 29;115(17):3472-80.
  17. Song Y, Bahnson A, Hall N, Yu H, Shen H, Koebler D, Houck R, Xie Y, Cheng T. Stem cell traits in long-term co-culture revealed by time-lapse imaging. Leukemia. 2010 Jan;24(1):153-61.
  18. XuFeng R, Boyer MJ, Shen H, Li Y, Yu H, Gao Y, Yang Q, Wang Q, Cheng T. ADAR1 is required for survival of hematopoietic progenitors but not primitive stem cells via RNA editing. Proc Natl Acad Sci USA 2009;106(42):17763-8
  19. Hu XX, Shen HM, Tian C, Yu H, Zheng GG, XuFeng R, Ju ZY, Xu J, Wang JM, Cheng T. Kinetics of normal hematopoietic stem and progenitor cells in a Notch1-induced leukemia model. Blood, 2009;114(18):3783-3792.
  20. Qiu J, Takagi Y, Harada J, Topalkara K, Wang Y, Sims JR, Zheng G, Huang P, Ling Y, Scadden DT, Moskowitz MA,Cheng T. p27Kip1 constrains proliferation of neural progenitor cells in adult brain under homeostatic and ischemic conditions. Stem Cells. 2009; 27(4):920-927.
  21. Sung L, Gao S, Shen H, Yu H, Song Y, Smith S, Chang C, Inoue, Kuo L, Lian J, Li A, Tian X, Tuck D, Weissman S, Yang X, and Cheng T. Differentiated cells are more efficient than adult stem cells as donors for cloning by somatic cell nuclear transfer. Nature Genetics 2006 Nov;38(11):1323-8.
  22. Yuan Y, Yu H, Boyer M, Shen H, Cao S and Cheng T.  Hematopoietic stem cells are not the direct target of spontaneous leukemic transformation in p18INK4C-null reconstituted mice.  Cancer Research 2006 Jan;24(1):48-52.
  23. Yu H, Yuan Y, Shen H, and Cheng T.   Hematopoietic stem cell exhaustion impacted by p18 and p21 in opposite manners.  Blood. 2006 Feb 1;107(3):1200-6.
  24. Yuan Y, Shen H, Franklin DS, Scadden DT and Cheng T.  Self-renewing divisions of hematopoietic stem cells in vivo are increased in the absence of the early G1-phase inhibitor, p18INK4c.  Nature Cell Biology 2004 May; 6(5): 436-42.
  25. Qiu JH, Takagi Y, Harada J, Rodrigues N, Moskowitz MA, Scadden DT and Cheng T.  Regenerative response in ischemic brain restricted by p21.  Journal of Experimental Medicine 2004 Apr 5;199(7):937-45.
  26. Cheng T, Shen H, Rodrigues N, Stier S and Scadden DT.  Transforming growth factor beta1 mediates cell-cycle arrest of primitive hematopoietic cells independent of p21(Cip1/Waf1) or p27(Kip1).  Blood. 2001 Dec 15;98(13):3643-3649.
  27. Cheng T, Rodrigues N, Shen H, Yong-guang Yang, Dombkowski D, Sykes M and Scadden DT.  Hematopoietic stem cell quiescence in vivo is maintained by p21.  Science 2000; 287: 1804-1808.
  28. Cheng T, Rodrigues N, Dombkowski D, Stier S and Scadden DT.  Stem cell repopulation efficiency is governed by the CDK inhibitor, p27.  Nature Medicine 2000; 6 1236-40.

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